SCHEMBL28565752

SCHEMBL28565752

CCCCC=CCCc1cc(O)ccc1C(=O)OCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.54
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA7 P43166 3/20 0.54
CA9 Q16790 3/20 0.54
CA14 Q9ULX7 3/20 0.54
EGFR P00533 2/20 0.44
SERPINE1 P05121 1/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MIF P14174 1/20 0.41
PFKFB3 Q16875 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MAPT P10636 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28537883 0.86 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL127366 0.84 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL1193719 0.83 CA12 (0.66) CA12CA1CA2CA7CA9
SCHEMBL542402 0.79 CA12 (0.72) CA12CA1CA2CA7CA9
SCHEMBL10006039 0.77 TSHR (0.56) CA12CA1CA2CA7CA9
SCHEMBL29029490 0.77 TSHR (0.56) CA12CA1CA2CA7CA9
SCHEMBL2584734 0.77 SERPINE1 (0.55) CA12CA1CA2CA7CA9
SCHEMBL24922984 0.75 CA12 (0.66) CA12CA1CA2CA7CA9
SCHEMBL5317593 0.75 TSHR (0.57) SERPINE1LMNAMEN1TP53KMT2A
SCHEMBL25393746 0.75 TSHR (0.57) SERPINE1LMNAMEN1TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104487581-B Enzymes and methods for styrene synthesis 菲特吉恩公司 2021-05-28 CN disclosed