SCHEMBL5317593

SCHEMBL5317593

CCCCCCCOC(=O)c1ccc(O)cc1CCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 2/20 0.57
TP53 P04637 2/20 0.55
CYP3A4 P08684 2/20 0.55
MAPK1 P28482 2/20 0.55
SERPINE1 P05121 1/20 0.53
MEN1 O00255 1/20 0.51
ALOX5 P09917 1/20 0.51
MAPT P10636 1/20 0.51
TYR P14679 1/20 0.51
ALOX15 P16050 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
KDM4E B2RXH2 1/20 0.51
POLB P06746 1/20 0.51
HSD17B10 Q99714 1/20 0.51
ESR1 P03372 3/20 0.50
AKR1C4 P17516 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29062899 1.00 TSHR (0.57) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL130709 1.00 TSHR (0.57) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL28450761 1.00 TSHR (0.57) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL29285270 1.00 TSHR (0.57) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL6035520 0.97 TSHR (0.57) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL27533460 0.97 TSHR (0.57) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL9436087 0.92 TSHR (0.60) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL10006039 0.92 TSHR (0.56) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL127366 0.90 CA12 (0.59) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL29029490 0.89 TSHR (0.56) TSHRALDH1A1LMNATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1328165-B1 METHOD FOR PREPARING CALCIUM-SUPPLEMENTED BEVERAGES PEPSICO INC (US) 2007-10-10 EP claimed