Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 4/20 | 0.67 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568911 | 0.92 | VEGFA (0.69) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL28571945 | 0.90 | VEGFA (0.69) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL17005931 | 0.89 | VEGFA (0.52) | VEGFAEGLN1ALDH1A1KDM4EPOLB | |
| SCHEMBL17005947 | 0.89 | VEGFA (0.52) | VEGFAEGLN1ALDH1A1KDM4EPOLB | |
| SCHEMBL28573781 | 0.86 | VEGFA (0.68) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL28586368 | 0.85 | VEGFA (0.71) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL17005960 | 0.85 | VEGFA (0.56) | VEGFAEGLN1ALDH1A1KDM4E | |
| SCHEMBL28568931 | 0.85 | VEGFA (0.73) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL28576404 | 0.85 | VEGFA (0.67) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL28571955 | 0.85 | VEGFA (0.67) | VEGFAEGLN1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |