Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 4/20 | 0.73 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770463 | 0.92 | VEGFA (0.75) | VEGFAEGLN1ALDH1A1MGLLKDM4E | |
| SCHEMBL28563641 | 0.90 | VEGFA (0.75) | VEGFAEGLN1ALDH1A1MGLLALOX15 | |
| SCHEMBL17005944 | 0.89 | VEGFA (0.57) | VEGFAEGLN1ALDH1A1MGLLALOX15 | |
| SCHEMBL17005953 | 0.89 | ALDH1A1 (0.61) | VEGFAEGLN1ALDH1A1ALOX15TDP1 | |
| SCHEMBL28573781 | 0.86 | VEGFA (0.68) | VEGFAEGLN1ALDH1A1MGLLKDM4E | |
| SCHEMBL28586368 | 0.85 | VEGFA (0.71) | VEGFAEGLN1ALDH1A1TDP1KDM4E | |
| SCHEMBL17309749 | 0.85 | VEGFA (0.83) | VEGFAEGLN1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL17005919 | 0.85 | VEGFA (0.59) | VEGFAEGLN1ALDH1A1KDM4EPOLB | |
| SCHEMBL28571955 | 0.85 | VEGFA (0.67) | VEGFAEGLN1ALDH1A1KDM4EPOLB | |
| SCHEMBL28576404 | 0.85 | VEGFA (0.67) | VEGFAEGLN1ALDH1A1MGLLALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |