Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 5/20 | 0.82 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579853 | 0.91 | VEGFA (0.74) | VEGFAEGLN1ALDH1A1MMP1MMP9 | |
| Izilendustat SCHEMBL1770480 | 0.90 | VEGFA (1.00) | VEGFAEGLN1ALDH1A1KDM1ASMN1; SMN2 | |
| SCHEMBL28562999 | 0.90 | VEGFA (0.85) | VEGFAEGLN1KDM1AMAPTLMNA | |
| SCHEMBL17005887 | 0.90 | VEGFA (0.66) | VEGFAEGLN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28563647 | 0.89 | VEGFA (0.83) | VEGFAEGLN1KDM1ACA12CA1 | |
| SCHEMBL28567361 | 0.89 | VEGFA (0.83) | VEGFAEGLN1ALDH1A1MMP1MMP9 | |
| SCHEMBL1770282 | 0.89 | VEGFA (0.83) | VEGFAEGLN1ALDH1A1KDM1A | |
| SCHEMBL17309749 | 0.89 | VEGFA (0.83) | VEGFAEGLN1ALDH1A1MAPT | |
| SCHEMBL28572828 | 0.89 | VEGFA (0.70) | VEGFAEGLN1ALDH1A1MAPTLMNA | |
| SCHEMBL17005929 | 0.88 | VEGFA (0.63) | VEGFAEGLN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |