Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 5/20 | 0.74 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.74 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572828 | 0.92 | VEGFA (0.70) | VEGFAEGLN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28566307 | 0.91 | VEGFA (0.82) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL17005938 | 0.90 | VEGFA (0.59) | VEGFAEGLN1MGLLALDH1A1MAPT | |
| SCHEMBL28567368 | 0.88 | VEGFA (0.77) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL17005872 | 0.88 | VEGFA (0.57) | VEGFAEGLN1ALDH1A1MAPTTDP1 | |
| SCHEMBL28566294 | 0.87 | VEGFA (0.85) | VEGFAEGLN1ALDH1A1KDM4ECA12 | |
| SCHEMBL28562994 | 0.87 | VEGFA (0.75) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL28586421 | 0.87 | VEGFA (0.75) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL28563655 | 0.87 | VEGFA (0.75) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL17005892 | 0.87 | VEGFA (0.58) | VEGFAEGLN1ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |