Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754835 | 0.79 | PRKAB2 (0.54) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31487914 | 0.76 | MAPT (0.38) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL3772458 | 0.76 | PRKAB2 (0.37) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL13960990 | 0.76 | KDR (0.37) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15333581 | 0.72 | POLB (0.43) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1991834 | 0.72 | CDK2 (0.53) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL19265949 | 0.72 | PRKAB2 (0.37) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL30749069 | 0.72 | PLK4 (0.35) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL18397071 | 0.72 | MAPT (0.35) | MAOBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16461023 | 0.71 | MAP4K4 (0.39) | MAP4K4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574211-B | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112574211-A | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2021-03-30 | — | — | CN | disclosed |