SCHEMBL28566366

SCHEMBL28566366

Fc1ccc2c(c1-c1cc3ccccc3o1)Cc1ccccc1O2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.39
MAOA P21397 4/20 0.39
AHR P35869 2/20 0.36
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
ADRA2A P08913 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
MAPKAPK2 P49137 1/20 0.34
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28566417 0.85 MAOB (0.39) MAOBMAOACHRM2CHRM4CHRM5
SCHEMBL28557268 0.82 MAOB (0.36) MAOBMAOACHRM2CHRM4CHRM5
SCHEMBL28559345 0.80 MAOB (0.49) MAOBMAOACHRM2CHRM4CHRM5
SCHEMBL11613016 0.72 MAOB (0.41) MAOBMAOAHPGDKDM4EALDH1A1
SCHEMBL5782439 0.68 MAOA (0.59) MAOBMAOAAHRMAPKAPK2ALOX5
SCHEMBL7657314 0.68 MAOB (0.43) MAOBMAOACHRM2CHRM4CHRM5
SCHEMBL29038655 0.67 MAOB (0.53) MAOBMAOACHRM2CHRM4CHRM5
SCHEMBL28232758 0.67 NPC1 (0.47) MAOBMAOAAHRCHRM2CHRM4
SCHEMBL13651411 0.66 NPC1 (0.59) MAOBMAOACHRM2CHRM4CHRM5
SCHEMBL79264 0.66 MAOA (0.55) MAOBMAOAHPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851652-B Catalytic oxidation synthesis method of 2- (substituted xanthyl) benzofuran compound 浙江工业大学 2022-06-14 CN disclosed
CN-112851652-A Catalytic oxidation synthesis method of 2- (substituted xanthyl) benzofuran compound 浙江工业大学 2021-05-28 CN disclosed