Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560945 | 0.92 | KMT2A (0.32) | KMT2AACACB | |
| SCHEMBL28566752 | 0.90 | KDM4E (0.33) | KMT2AMAPTACACBFFAR1 | |
| SCHEMBL28574863 | 0.88 | CHEK2 (0.31) | KMT2A | |
| SCHEMBL28559852 | 0.88 | ACACB (0.33) | KMT2APOLBACACB | |
| SCHEMBL28912534 | 0.84 | KMT2A (0.33) | KMT2AACACB | |
| SCHEMBL28913329 | 0.83 | KMT2A (0.32) | KMT2APOLBACACB | |
| SCHEMBL28559226 | 0.83 | ACACB (0.33) | KMT2AACACB | |
| SCHEMBL28912535 | 0.83 | KMT2A (0.32) | KMT2AACACB | |
| SCHEMBL28550607 | 0.82 | ACACB (0.32) | KMT2AACACB | |
| SCHEMBL18322953 | 0.81 | KMT2A (0.31) | KMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847765-B | 1, 4-substituted piperidine derivatives | 89生物有限公司 | 2021-05-04 | — | — | CN | disclosed |