Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 2/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560945 | 0.93 | KMT2A (0.32) | KMT2ACHEK2NEK2EPHX2HRH3 | |
| SCHEMBL28574863 | 0.91 | CHEK2 (0.31) | KMT2ACHEK2NEK2EPHX2HRH3 | |
| SCHEMBL28559852 | 0.91 | ACACB (0.33) | KMT2AACACB | |
| SCHEMBL28566527 | 0.90 | KMT2A (0.34) | MAPTKMT2AACACBFFAR1 | |
| SCHEMBL28913329 | 0.88 | KMT2A (0.32) | KMT2ACHEK2NEK2EPHX2HRH3 | |
| SCHEMBL28912534 | 0.86 | KMT2A (0.33) | KMT2ANEK2ACACB | |
| SCHEMBL28559226 | 0.86 | ACACB (0.33) | KMT2ACHEK2EPHX2HRH3ACACB | |
| SCHEMBL28550607 | 0.84 | ACACB (0.32) | KMT2ACHEK2EPHX2HRH3ACACB | |
| SCHEMBL28912545 | 0.84 | ACACB (0.34) | KMT2ANEK2EPHX2HRH3ACACB | |
| SCHEMBL28912535 | 0.84 | KMT2A (0.32) | KMT2ACHEK2NEK2EPHX2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847765-B | 1, 4-substituted piperidine derivatives | 89生物有限公司 | 2021-05-04 | — | — | CN | disclosed |