SCHEMBL28567015

SCHEMBL28567015

Cc1noc(-c2ccc(Br)cn2)c1C[C]1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLCO1B1 Q9Y6L6 1/20 0.34
LPAR1 Q92633 4/20 0.33
MBOAT4 Q96T53 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GABRA5 P31644 1/20 0.32
SPR P35270 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28560647 0.85 SLCO1B1 (0.38) SLCO1B1LPAR1CYP2C9
SCHEMBL25402932 0.81 TDP1 (0.39) SLCO1B1LPAR1CYP1A2CYP3A4CYP2C9
SCHEMBL29517555 0.81 CYP1A2 (0.38) MBOAT4CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL21807854 0.81 CYP1A2 (0.38) MBOAT4CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL21807777 0.80 CYP1A2 (0.37) SLCO1B1LPAR1MBOAT4CYP1A2CYP3A4
SCHEMBL22467452 0.80 CYP1A2 (0.37) MBOAT4CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL22230642 0.78 DGAT1 (0.40) SLCO1B1LPAR1
SCHEMBL28560210 0.74
SCHEMBL22467487 0.74 KDM4C (0.35) SLCO1B1LPAR1GABRA5
SCHEMBL29869171 0.74 KDM4C (0.35) SLCO1B1LPAR1GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112771027-B Lysophosphatidic acid receptor antagonists and process for preparing the same 武汉朗来科技发展有限公司 2024-03-05 CN disclosed
CN-112771027-A Lysophosphatidic acid receptor antagonists and process for their preparation 武汉朗来科技发展有限公司 2021-05-07 CN disclosed