Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607843 | 0.88 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL3607848 | 0.88 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL11158645 | 0.86 | SLC6A4 (0.64) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL28265941 | 0.86 | SLC6A4 (0.64) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL11732636 | 0.85 | SLC6A4 (0.62) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL11732629 | 0.85 | SLC6A4 (0.62) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL29067215 | 0.83 | TAAR1 (0.65) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL2058611 | 0.82 | CYP3A4 (0.61) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL28561355 | 0.81 | CYP3A4 (0.59) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL28561354 | 0.81 | CYP3A4 (0.59) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159401-B | Biased agonist and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-06-03 | — | — | CN | disclosed |
| CN-112159401-A | Biased agonist and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-01-01 | — | — | CN | disclosed |