SCHEMBL3607848

SCHEMBL3607848

NC(Cc1ccc2c(c1)OCO2)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.66
TAAR1 Q96RJ0 4/20 0.62
SLC6A2 P23975 2/20 0.62
SLC6A3 Q01959 2/20 0.62
CYP3A4 P08684 4/20 0.58
CYP2D6 P10635 2/20 0.58
ALDH1A1 P00352 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C19 P33261 1/20 0.56
SLC7A5 Q01650 3/20 0.55
KDM4E B2RXH2 1/20 0.55
USP2 O75604 1/20 0.55
EGFR P00533 1/20 0.55
LCK P06239 1/20 0.55
FYN P06241 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
ALOX15 P16050 1/20 0.55
PTGS1 P23219 1/20 0.55
HTR2A P28223 1/20 0.55
PTGS2 P35354 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3607843 1.00 SLC6A4 (0.66) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
Hydrochloric Acid SCHEMBL28265941 0.98 SLC6A4 (0.64) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
Hydrochloric Acid SCHEMBL11158645 0.98 SLC6A4 (0.64) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
Trifluoroacetic Acid SCHEMBL28868211 0.92 SLC6A4 (0.56) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
SCHEMBL3788967 0.91 SLC7A5 (0.55) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
SCHEMBL1744966 0.91 SLC7A5 (0.55) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
Hydrochloric Acid SCHEMBL27577123 0.90 SLC6A4 (0.54) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
Hydrochloric Acid SCHEMBL27577124 0.90 SLC6A4 (0.54) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
SCHEMBL28567121 0.88 SLC6A4 (0.66) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4
SCHEMBL10888091 0.87 SLC6A4 (0.51) SLC6A4TAAR1SLC6A2SLC6A3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110655500-B Carbamate derivatives, preparation method and application thereof 浙江京新药业股份有限公司 2020-12-08 CN claimed
CN-110655500-A Carbamate derivatives, preparation method and application thereof 浙江京新药业股份有限公司 2020-01-07 CN claimed
US-6232305-B1 ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS NAEJA PHARMACEUTICAL INC. (CA) 2001-05-15 US claimed
EP-0950046-A1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS SYNPHAR LABORATORIES INC. (CA) 1999-10-20 EP claimed
WO-1998012176-A1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS SYNPHAR LABORATORIES INC. (US) 1998-03-26 WO claimed
JP-62289194-A None JP disclosed
EP-4731211-A1 ALLYL- AND PROPARGYLAMINE-TYPE PHENETHYLAMINES AND TRYPTAMINES FOR TREATING MEDICAL DISORDERS Definium Therapeutics US, Inc. (US) 2026-04-29 EP disclosed
US-20250312309-A1 ALLYL-AND PROPARGYLAMINE-TYPE PHENETHYLAMINES AND TRYPTAMINES FOR TREATING MEDICAL DISORDERS Mind Medicine, Inc. (US) 2025-10-09 US disclosed
WO-2024263978-A1 ALLYL- AND PROPARGYLAMINE-TYPE PHENETHYLAMINES AND TRYPTAMINES FOR TREATING MEDICAL DISORDERS Mind Medicine, Inc. (US) 2024-12-26 WO disclosed
US-10864253-B2 Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage ARAIM PHARMACEUTICALS, INC. (US) 2020-12-15 US disclosed
CN-110655500-B Carbamate derivatives, preparation method and application thereof 浙江京新药业股份有限公司 2020-12-08 CN disclosed
CN-110655500-A Carbamate derivatives, preparation method and application thereof 浙江京新药业股份有限公司 2020-01-07 CN disclosed
US-4562263-A HYPOTENSIVE AND HYDERTENSIVE AGENTS, ANTIDEPRESSANTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-31 US disclosed
EP-0084928-B1 PROCESS FOR PRODUCING THREO-3-(3,4-DIHYDROXYPHENYL)SERINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-11 EP disclosed
EP-0128684-A1 Process for producing 3-(3,4-dihydroxyphenyl) serine SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1984-12-19 EP disclosed
US-4480109-A Process for producing threo-3-(3,4-dihydroxyphenyl)serine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-10-30 US disclosed
EP-0084928-A1 Process for producing threo-3-(3,4-dihydroxyphenyl)serine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-08-03 EP disclosed
US-4020060-A ANTIBACTERIAL, ANTIBIOTICS RICHARDSON-MERRELL INC. (US) 1977-04-26 US disclosed
US-4016037-A FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES AJINOMOTO CO., INC. (JA) 1977-04-05 US disclosed
US-3994877-A 6-[α-AMINO-ω-(3,4-METHYLENEDIOXYPHENYL)ACYLAMIDO]PENICILLANIC ACID DERIVATIVES RICHARDSON-MERRELL INC. (US) 1976-11-30 US disclosed