Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 5/20 | 0.77 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.77 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913769 | 0.91 | VEGFA (0.73) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28562999 | 0.91 | VEGFA (0.85) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28566294 | 0.89 | VEGFA (0.85) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28570561 | 0.89 | VEGFA (0.79) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28586421 | 0.89 | VEGFA (0.75) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28562994 | 0.89 | VEGFA (0.75) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28563655 | 0.89 | VEGFA (0.75) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL17005912 | 0.89 | VEGFA (0.60) | VEGFAEGLN1GPR183 | |
| SCHEMBL17005970 | 0.89 | VEGFA (0.60) | VEGFAEGLN1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28579853 | 0.88 | VEGFA (0.74) | VEGFAEGLN1IDO1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |