SCHEMBL28567458

SCHEMBL28567458

CCCC(CNC(C#N)CC)CC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSC P53634 4/20 0.35
GPR84 Q9NQS5 4/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CTSH P09668 1/20 0.31
CYP2D6 P10635 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28567457 1.00 CTSC (0.35) CTSCGPR84CYP1A2CYP3A4CTSH
SCHEMBL28577695 0.83 CACNA2D1 (0.33) GPR84
SCHEMBL28561981 0.80 CTSK (0.38) CYP2D6CTSK
SCHEMBL28575568 0.80 CTSK (0.38) CYP2D6CTSK
SCHEMBL21881963 0.80 CTSK (0.38) CYP2D6CTSK
SCHEMBL28575572 0.80 CTSK (0.38) CYP2D6CTSK
SCHEMBL23311182 0.77 KDM4E (0.36) GPR84
SCHEMBL2324298 0.76 CHRM1 (0.36) GPR84
SCHEMBL2324304 0.76 CHRM1 (0.36) GPR84
SCHEMBL21602737 0.73 CA1 (0.33) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112739683-A Preparation method and intermediate of brivaracetam 上海宣泰医药科技股份有限公司 2021-04-30 CN disclosed