SCHEMBL28567480

SCHEMBL28567480

Nc1cc(S(=O)(=O)O)c(N)cc1S(=O)(=O)O.[NaH]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.45
NQO1 P15559 1/20 0.43
ALDH1A1 P00352 8/20 0.41
HSD17B10 Q99714 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
CASP6 P55212 3/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TSHR P16473 3/20 0.39
NT5E P21589 2/20 0.39
RAPGEF4 Q8WZA2 1/20 0.38
AURKA O14965 1/20 0.38
AURKB Q96GD4 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1412987 0.97 TTR (0.46) TTRNQO1ALDH1A1HSD17B10TDP1
Nitrogen SCHEMBL28715481 0.92 TTR (0.43) TTRNQO1ALDH1A1HSD17B10TDP1
SCHEMBL8829810 0.92 TTR (0.43) TTRNQO1ALDH1A1HSD17B10TDP1
SCHEMBL10870494 0.92 TTR (0.43) TTRNQO1ALDH1A1HSD17B10TDP1
SCHEMBL427123 0.89 TTR (0.45) TTRNQO1ALDH1A1HSD17B10TDP1
Ammonia Solution, Strong SCHEMBL7550094 0.86 TTR (0.43) TTRNQO1ALDH1A1HSD17B10TDP1
Ammonia Solution, Strong SCHEMBL7550098 0.86 TTR (0.43) TTRNQO1ALDH1A1HSD17B10TDP1
SCHEMBL9310126 0.85 ALDH1A1 (0.50) TTRNQO1ALDH1A1HSD17B10TDP1
SCHEMBL7549756 0.84 ALDH1A1 (0.42) TTRNQO1ALDH1A1HSD17B10TDP1
SCHEMBL3503572 0.84 ALDH1A1 (0.42) TTRNQO1ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112852185-B Blue fluorine-containing reactive dye with high fixation rate and preparation method thereof 湖北丽源科技股份有限公司 2022-08-05 CN disclosed
CN-112852185-A Blue fluorine-containing reactive dye with high fixation rate and preparation method thereof 湖北丽源科技股份有限公司 2021-05-28 CN disclosed