Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.57 |
| ▸ | HTR2C | P28335 | 13/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857218 | 0.80 | PIK3CA (0.74) | PIK3CAHTR2C | |
| SCHEMBL2878573 | 0.79 | PIK3CA (0.62) | PIK3CAHTR2CALDH1A1POLB | |
| SCHEMBL2878746 | 0.77 | HTR2C (0.61) | PIK3CAHTR2CALDH1A1POLB | |
| SCHEMBL2805981 | 0.74 | HTR2C (0.98) | PIK3CAHTR2C | |
| SCHEMBL2856457 | 0.74 | PIK3CA (0.52) | PIK3CAHTR2CALDH1A1POLB | |
| SCHEMBL13944361 | 0.73 | PIK3CA (1.00) | PIK3CAHTR2C | |
| SCHEMBL3755710 | 0.73 | HTR2C (1.00) | PIK3CAHTR2C | |
| SCHEMBL2861201 | 0.73 | PIK3CA (0.46) | PIK3CAHTR2CPOLB | |
| SCHEMBL2786916 | 0.73 | PIK3CA (0.51) | PIK3CAHTR2CALDH1A1POLB | |
| SCHEMBL13947043 | 0.72 | PIK3CA (0.79) | PIK3CAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |