Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.59 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859459 | 0.90 | HTR2C (0.49) | HTR2CPIK3CAMAPK14GBA1 | |
| SCHEMBL2786916 | 0.81 | PIK3CA (0.51) | HTR2CPIK3CAMAPK14ALDH1A1POLB | |
| SCHEMBL13943299 | 0.79 | HTR2C (0.88) | HTR2CPIK3CA | |
| SCHEMBL2878573 | 0.79 | PIK3CA (0.62) | HTR2CPIK3CAALDH1A1POLB | |
| SCHEMBL2857218 | 0.78 | PIK3CA (0.74) | HTR2CPIK3CA | |
| SCHEMBL13943726 | 0.77 | HTR2C (0.66) | HTR2CPIK3CAALDH1A1 | |
| SCHEMBL3754974 | 0.77 | HTR2C (1.00) | HTR2CPIK3CA | |
| SCHEMBL2856769 | 0.77 | PIK3CA (0.57) | HTR2CPIK3CAALDH1A1POLB | |
| SCHEMBL3761166 | 0.75 | HTR2C (1.00) | HTR2CPIK3CAATAD2 | |
| SCHEMBL13944361 | 0.74 | PIK3CA (1.00) | HTR2CPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |