Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | GCGR | P47871 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562690 | 0.88 | HDAC6 (0.64) | HDAC6HDAC8HDAC11GCGRHDAC3 | |
| SCHEMBL30185530 | 0.88 | HDAC6 (0.64) | HDAC6HDAC8HDAC11GCGRHDAC3 | |
| SCHEMBL30364815 | 0.85 | GCGR (0.52) | HDAC6HDAC8HDAC11GCGRHDAC3 | |
| SCHEMBL28573537 | 0.85 | HDAC6 (0.76) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL30185513 | 0.82 | HDAC8 (0.68) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL7014848 | 0.82 | HDAC8 (0.68) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL28586563 | 0.81 | HDAC6 (0.60) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL28565908 | 0.81 | HDAC6 (0.67) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL15971036 | 0.81 | PLAU (0.57) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL30888879 | 0.81 | PLAU (0.57) | HDAC6HDAC8HDAC11HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-112759541-A | Indole-like derivatives and uses thereof | 复旦大学 | 2021-05-07 | — | — | CN | disclosed |