Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.68 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014848 | 1.00 | HDAC8 (0.68) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL28310548 | 0.89 | HDAC8 (0.55) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL28565908 | 0.87 | HDAC6 (0.67) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL15971036 | 0.87 | PLAU (0.57) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL30888879 | 0.87 | PLAU (0.57) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL30790906 | 0.86 | HDAC8 (0.53) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL28563193 | 0.86 | HDAC6 (0.68) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL14120940 | 0.86 | HDAC6 (0.57) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL28774000 | 0.86 | HDAC8 (0.53) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL6705753 | 0.84 | HDAC6 (0.66) | HDAC8HDAC6HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |