Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | DDT | P30046 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856831 | 1.00 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2852365 | 0.87 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2856640 | 0.86 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2854567 | 0.85 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2858895 | 0.85 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2857950 | 0.84 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2196550 | 0.84 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2196554 | 0.84 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2859964 | 0.83 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2850785 | 0.83 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828148-B1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-01-20 | — | — | EP | claimed |
| EP-1828148-A1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | Leo Pharma A/S (DK) | 2007-09-05 | — | — | EP | claimed |
| WO-2006063585-A1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA A/S (DK) | 2006-06-22 | — | — | WO | claimed |
| US-20060128766-A1 | Triazole substituted aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-06-15 | — | — | US | claimed |
| US-8293772-B2 | Triazole substituted aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2012-10-23 | — | — | US | disclosed |
| EP-1828148-B1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-01-20 | — | — | EP | disclosed |
| EP-1828148-A1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | Leo Pharma A/S (DK) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063585-A1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA A/S (DK) | 2006-06-22 | — | — | WO | disclosed |
| US-20060128766-A1 | Triazole substituted aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128766-A1 | Triazole substituted aminobenzophenone compounds | NFKBIA, UACA, CYP1B1 | MAPK13 1436/4885MAPK12 1829/4885MAPK11 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.