SCHEMBL28568397

SCHEMBL28568397

Cc1ccc(C=O)c(NC(=O)c2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 2/20 0.66
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
MAPT P10636 3/20 0.53
POLB P06746 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
HPGD P15428 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PKM P14618 1/20 0.51
GRIK1 P39086 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
GFER P55789 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
HDAC2 Q92769 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28578326 0.88 KCNMA1 (0.61) KCNMA1MEN1KMT2AMAPTPOLB
SCHEMBL14428369 0.84 MEN1 (0.50) KCNMA1MEN1KMT2AMAPTPOLB
SCHEMBL14428398 0.83 MEN1 (0.53) KCNMA1MEN1KMT2AMAPTPOLB
SCHEMBL16317646 0.82 KCNMA1 (0.76) KCNMA1MEN1KMT2AMAPTPOLB
SCHEMBL14428165 0.82 HDAC2 (0.66) MEN1KMT2AMAPTPKMGRIK1
SCHEMBL14428442 0.82 MAPT (0.51) KCNMA1MEN1KMT2AMAPTPOLB
SCHEMBL14428216 0.82 MAPT (0.58) MEN1KMT2AMAPTHPGDPKM
SCHEMBL28574210 0.81 SNCA (0.61) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL5310996 0.81 KCNMA1 (0.73) KCNMA1MEN1KMT2AMAPTPOLB
SCHEMBL30758797 0.80 SNCA (0.59) MEN1KMT2AMAPTPOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110218137-B Synthetic method of anthranilic aldehyde compound 上海交通大学 2021-01-22 CN disclosed