Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 13/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 11/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722901 | 0.83 | DPP4 (0.45) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL30061913 | 0.83 | DPP4 (0.45) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL30968546 | 0.83 | PARP1 (0.38) | GPR119DPP4RIPK1KDM4EMAPT | |
| SCHEMBL21685838 | 0.79 | JAK1 (0.44) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL30968534 | 0.79 | JAK1 (0.44) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL20722594 | 0.72 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL28574169 | 0.72 | ALDH1A1 (0.43) | NR1H2NR1H3MAPTTHRB | |
| SCHEMBL17114699 | 0.69 | MAPT (0.41) | NR1H2NR1H3GPR119MAPT | |
| SCHEMBL17114700 | 0.69 | MAPT (0.41) | NR1H2NR1H3GPR119MAPT | |
| SCHEMBL21685827 | 0.68 | JAK1 (0.41) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |