Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30410753 | 1.00 | DHPS (0.79) | DHPS | |
| SCHEMBL28584109 | 0.92 | DHPS (0.65) | DHPS | |
| SCHEMBL28577292 | 0.88 | DHPS (1.00) | DHPS | |
| SCHEMBL30412354 | 0.88 | DHPS (1.00) | DHPS | |
| SCHEMBL30410739 | 0.88 | DHPS (1.00) | DHPS | |
| SCHEMBL28578002 | 0.88 | DHPS (1.00) | DHPS | |
| SCHEMBL28566926 | 0.87 | DHPS (1.00) | DHPS | |
| SCHEMBL30411286 | 0.87 | DHPS (1.00) | DHPS | |
| SCHEMBL30411986 | 0.87 | DHPS (1.00) | DHPS | |
| SCHEMBL29015748 | 0.87 | DHPS (1.00) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898208-A | Phenyl pyrimidinamine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-06-04 | — | — | CN | claimed |
| CN-112778215-B | 2-methoxyphenoxypyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112898208-B | Phenylpyrimidine amine antitumor compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112898208-A | Phenyl pyrimidinamine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-112778215-A | 2-methoxyphenoxy pyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-05-11 | — | — | CN | disclosed |