Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483990 | 0.77 | PARP10 (0.43) | PARP10TDP1L3MBTL1PARP1PNMT | |
| SCHEMBL598138 | 0.74 | TDP1 (0.61) | PARP10TDP1L3MBTL1PARP1PNMT | |
| SCHEMBL22685320 | 0.73 | TDP1 (0.38) | PARP10TDP1L3MBTL1PARP1TDP2 | |
| SCHEMBL769170 | 0.73 | PARP10 (0.40) | PARP10TDP1L3MBTL1PARP1PNMT | |
| SCHEMBL6097069 | 0.73 | PARP10 (0.40) | PARP10TDP1L3MBTL1PARP1PNMT | |
| SCHEMBL27710326 | 0.73 | PARP10 (0.44) | PARP10TDP1L3MBTL1PARP1PNMT | |
| SCHEMBL14059486 | 0.72 | TDP1 (0.54) | PARP10TDP1L3MBTL1PARP1TYMS | |
| SCHEMBL31375435 | 0.71 | CES1 (0.43) | PARP10L3MBTL1PARP1PARP11 | |
| SCHEMBL6244296 | 0.71 | CES1 (0.43) | PARP10L3MBTL1PARP1PARP11 | |
| SCHEMBL29582639 | 0.71 | MAOB (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979412-B | Preparation method of 7-bromo-1-chloronaphthalene | 江苏丽源医药有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-112979412-A | Preparation method of 7-bromo-1-chloronaphthalene | 江苏丽源医药有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-112979412-B | Preparation method of 7-bromo-1-chloronaphthalene | 江苏丽源医药有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112979412-B | Preparation method of 7-bromo-1-chloronaphthalene | 江苏丽源医药有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112979412-A | Preparation method of 7-bromo-1-chloronaphthalene | 江苏丽源医药有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112979412-A | Preparation method of 7-bromo-1-chloronaphthalene | 江苏丽源医药有限公司 | 2021-06-18 | — | — | CN | disclosed |