Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358939 | 0.85 | TDP1 (0.81) | TDP1L3MBTL1PARP10PARP1TYMS | |
| SCHEMBL27286 | 0.84 | PBRM1 (0.64) | TDP1L3MBTL1PARP10PARP1TYMS | |
| SCHEMBL3362722 | 0.84 | TDP1 (0.52) | TDP1L3MBTL1PARP10PARP1PNMT | |
| SCHEMBL14053768 | 0.84 | TDP1 (0.52) | TDP1L3MBTL1PARP10PARP1PNMT | |
| SCHEMBL3165396 | 0.83 | CHEK2 (0.57) | TDP1L3MBTL1PARP10PARP1PNMT | |
| SCHEMBL12117371 | 0.81 | CHEK2 (0.55) | TDP1L3MBTL1PARP10PARP1PNMT | |
| SCHEMBL23264456 | 0.80 | L3MBTL1 (0.62) | TDP1L3MBTL1PARP10PARP1MAOA | |
| SCHEMBL13594 | 0.80 | — | — | |
| SCHEMBL4817935 | 0.79 | SRD5A1 (0.60) | TDP1L3MBTL1PARP10PARP1PNMT | |
| SCHEMBL18457167 | 0.79 | TDP1 (0.56) | TDP1L3MBTL1PARP10PARP1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114315-B2 | PHPIT and fabrication thereof | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2012-02-14 | — | — | US | disclosed |
| US-20100059714-A1 | PHPIT and fabrication thereof | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2010-03-11 | — | — | US | disclosed |