Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808119 | 1.00 | GFER (0.43) | GFERGAAKDM4EPOLBHSD17B10 | |
| SCHEMBL21820416 | 0.86 | NPC1 (0.44) | GFERGAAKDM4EHSD17B10KMT2A | |
| SCHEMBL21820526 | 0.86 | NPC1 (0.44) | GFERGAAKDM4EHSD17B10KMT2A | |
| SCHEMBL28904936 | 0.81 | ALDH1A1 (0.55) | POLBKMT2AL3MBTL1TP53MEN1 | |
| SCHEMBL28904938 | 0.81 | ALDH1A1 (0.55) | POLBKMT2AL3MBTL1TP53MEN1 | |
| SCHEMBL31390896 | 0.78 | KMT2A (0.36) | GAAKDM4EPOLBHSD17B10NR4A1 | |
| SCHEMBL21808171 | 0.76 | KDM4E (0.55) | GAAKDM4EPOLBHSD17B10NR4A1 | |
| SCHEMBL2774234 | 0.76 | KDM4E (0.61) | GFERGAAKDM4EPOLBHSD17B10 | |
| SCHEMBL28904928 | 0.73 | GFER (0.36) | GFERKMT2AHPGDNR1I2SMARCA2 | |
| SCHEMBL28904927 | 0.73 | GFER (0.36) | GFERKMT2AHPGDNR1I2SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215838-A | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112770745-B | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112770745-A | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2021-05-07 | — | — | CN | disclosed |