Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 12/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569497 | 1.00 | ATF4 (0.67) | ATF4LMNARAB9AHPGDHTT | |
| SCHEMBL30054459 | 1.00 | ATF4 (0.67) | ATF4LMNARAB9AHPGDHTT | |
| SCHEMBL24998317 | 1.00 | ATF4 (0.67) | ATF4LMNARAB9AHPGDHTT | |
| SCHEMBL28580887 | 0.91 | ATF4 (0.63) | ATF4LMNA | |
| SCHEMBL28580886 | 0.91 | ATF4 (0.63) | ATF4LMNA | |
| SCHEMBL28567281 | 0.91 | ATF4 (0.60) | ATF4LMNARAB9AHPGDHTT | |
| SCHEMBL28567286 | 0.91 | ATF4 (0.60) | ATF4LMNARAB9AHPGDHTT | |
| SCHEMBL30883092 | 0.91 | ATF4 (0.60) | ATF4LMNARAB9AHPGDHTT | |
| SCHEMBL16082976 | 0.91 | ATF4 (0.78) | ATF4LMNARAB9AHPGDHTT | |
| SCHEMBL23455918 | 0.89 | ATF4 (0.69) | ATF4LMNARAB9AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112166113-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-01-01 | — | — | CN | disclosed |