Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.58 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548453 | 0.85 | KDM4E (0.60) | ALDH1A1ARPOLBSMN1; SMN2LMNA | |
| SCHEMBL28556498 | 0.85 | ALDH1A1 (0.60) | ALDH1A1ARPOLBSMN1; SMN2LMNA | |
| SCHEMBL28566601 | 0.83 | CNR1 (0.56) | ALDH1A1ARPOLBSMN1; SMN2LMNA | |
| SCHEMBL16917804 | 0.83 | AR (0.55) | ALDH1A1ARGRM2POLBSMN1; SMN2 | |
| SCHEMBL19580338 | 0.83 | AR (0.55) | ALDH1A1ARPOLBSMN1; SMN2LMNA | |
| SCHEMBL8498625 | 0.83 | KMT2A (0.64) | ALDH1A1ARPOLBLMNAGFER | |
| Hydrochloric Acid SCHEMBL8112561 | 0.82 | AR (0.53) | ALDH1A1ARPOLBSMN1; SMN2LMNA | |
| SCHEMBL13753311 | 0.82 | AR (0.53) | ALDH1A1ARPOLBSMN1; SMN2LMNA | |
| SCHEMBL1773322 | 0.81 | CMA1 (0.60) | ALDH1A1ARPLA2G7POLBSMN1; SMN2 | |
| SCHEMBL13744964 | 0.81 | AR (0.56) | ALDH1A1ARPOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047925-B | Preparation method of N- (aryl/heteroaryl) alkyl-diamide | 中国科学院兰州化学物理研究所 | 2021-06-25 | — | — | CN | disclosed |
| CN-112047925-A | Preparation method of N- (aryl/heteroaryl) alkyl-diamide | 中国科学院兰州化学物理研究所 | 2020-12-08 | — | — | CN | disclosed |