Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560404 | 0.96 | BACE1 (0.35) | BACE1RENEPHX2KDM4EKMT2A | |
| SCHEMBL28559878 | 0.78 | FAAH (0.47) | FAAHSLC6A5MMP2EPHX2 | |
| SCHEMBL9807320 | 0.73 | PLA2G10 (0.46) | PLA2G10FAAHMMP2EPHX2PLA2G2A | |
| SCHEMBL28563738 | 0.72 | MME (0.43) | FAAHMMP2 | |
| SCHEMBL5351493 | 0.68 | FAAH (0.45) | FAAHMMP2EPHX2KDM4EKMT2A | |
| SCHEMBL8391655 | 0.67 | CYSLTR2 (0.49) | MMP2KDM4EKMT2AL3MBTL1 | |
| SCHEMBL8393308 | 0.67 | CYSLTR2 (0.49) | MMP2KDM4EKMT2AL3MBTL1 | |
| SCHEMBL28931476 | 0.66 | KMT2A (0.43) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL9185451 | 0.66 | CYP2C9 (0.50) | MMP2KDM4EKMT2AL3MBTL1 | |
| SCHEMBL2025362 | 0.66 | EPHX2 (0.47) | FAAHMMP2EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812149-B | Amino acid derivative, preparation method and application thereof, anti-tumor micelle and preparation method thereof | 首都医科大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-112812149-A | Amino acid derivative, preparation method and application thereof, anti-tumor micelle and preparation method thereof | 首都医科大学 | 2021-05-18 | — | — | CN | disclosed |