SCHEMBL28569685

SCHEMBL28569685

CCOC(=O)C(NC(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
SMN1; SMN2 Q16637 5/20 0.51
PRSS1 P07477 4/20 0.50
CTSG P08311 4/20 0.50
CTRB1 P17538 4/20 0.50
CMA1 P23946 4/20 0.50
NPC1 O15118 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
RAB9A P51151 3/20 0.49
GAA P10253 2/20 0.49
ALDH1A1 P00352 1/20 0.48
CYP26A1 O43174 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5784044 0.92 SMN1; SMN2 (0.55) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL9459929 0.89 SMN1; SMN2 (0.52) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL1968423 0.88 CA12 (0.55) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL11636179 0.88 CA12 (0.55) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL2486914 0.88 SMN1; SMN2 (0.51) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL8823156 0.87 NPC1 (0.48) CA12CA1CA2CA9SMN1; SMN2
Iodide SCHEMBL5351689 0.86 CA12 (0.54) CA12CA1CA2CA9SMN1; SMN2
Bromide SCHEMBL7614615 0.86 CA12 (0.54) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL3603034 0.84 SMN1; SMN2 (0.48) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL14724516 0.83 RAB9A (0.58) SMN1; SMN2NPC1RAB9AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661584-B Preparation method of photocatalytic N-alkyl amide compound 大连理工大学 2022-08-05 CN disclosed
CN-112661584-A Preparation method of photocatalytic N-alkyl amide compound 大连理工大学 2021-04-16 CN disclosed