Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574158 | 0.94 | CNR1 (0.47) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28579598 | 0.93 | CNR1 (0.46) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28584727 | 0.92 | CNR1 (0.46) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28584147 | 0.89 | CNR1 (0.48) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14194793 | 0.89 | TUBB4A (0.50) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4401484 | 0.88 | KDM4E (0.52) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29040460 | 0.86 | CNR1 (0.46) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30039404 | 0.85 | CNR1 (0.49) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29040411 | 0.85 | CNR1 (0.49) | CNR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28600184 | 0.85 | CNR1 (0.46) | CNR1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920208-B | Boric acid-containing indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-112898193-B | Indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-112920208-A | Boric acid-containing indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-112898193-A | Indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2021-06-04 | — | — | CN | disclosed |