Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678367 | 0.89 | HDAC10 (0.42) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7681166 | 0.89 | CXCL8 (0.56) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7680805 | 0.81 | HDAC10 (0.40) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL15641391 | 0.79 | PTGS1 (0.56) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL15641390 | 0.79 | PTGS1 (0.56) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL2739307 | 0.78 | CXCL8 (0.59) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7678196 | 0.77 | CXCL8 (0.46) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7676873 | 0.77 | HTT (0.44) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7678514 | 0.77 | CXCL8 (0.42) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL28851502 | 0.76 | CXCL8 (0.53) | CXCL8AKR1B1PTGS1PTGS2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661688-B | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112661688-A | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2021-04-16 | — | — | CN | disclosed |