Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474446 | 0.85 | PDE3A (0.53) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL27999217 | 0.84 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNATHRB | |
| Methyl Alcohol SCHEMBL27751480 | 0.84 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL3345909 | 0.84 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL23258348 | 0.81 | PDE3A (0.56) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL4750195 | 0.78 | PDE3A (0.51) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL587470 | 0.78 | PDE3A (0.53) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL587469 | 0.78 | PDE3A (0.53) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL27712544 | 0.78 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL4621563 | 0.77 | PDE3A (0.44) | PDE3APDE4DSLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112933103-B | Cytidine trifluoride and tipyrimidine hydrochloride combination and application | 江苏集萃分子工程研究院有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-112933103-A | Cytidine trifluoride and tipyrimidine hydrochloride combination and application | 江苏集萃分子工程研究院有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-112979721-B | Preparation method of high-purity antineoplastic medicine troflucytidine | 江苏集萃分子工程研究院有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-112933103-B | Cytidine trifluoride and tipyrimidine hydrochloride combination and application | 江苏集萃分子工程研究院有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-112933103-A | Cytidine trifluoride and tipyrimidine hydrochloride combination and application | 江苏集萃分子工程研究院有限公司 | 2021-06-11 | — | — | CN | disclosed |