Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712544 | 0.85 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL3474446 | 0.78 | PDE3A (0.53) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL28569717 | 0.77 | PDE3A (0.53) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL27999217 | 0.77 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNATHRB | |
| Methyl Alcohol SCHEMBL27751480 | 0.77 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL3345909 | 0.77 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL6060585 | 0.77 | LMNA (0.45) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL25407209 | 0.76 | LMNA (0.44) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL29597277 | 0.76 | PDE3A (0.44) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL31190163 | 0.76 | PDE4D (0.42) | PDE3APDE4DSLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128472-B | Process for fluorocytidine derivatives | HOFFMANN LA ROCHE | 2012-03-14 | — | — | CN | disclosed |
| EP-1706414-B1 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | disclosed |
| US-7365188-B2 | Process for producing N4-Acyl-5′-deoxy-5-fluorocytidine | ROCHE COLORADO CORPORATION (US) | 2008-04-29 | — | — | US | disclosed |
| CN-101128472-A | Process for fluorocytidine derivatives | ROCHE COLORADO CORP (CH) | 2008-02-20 | — | — | CN | disclosed |
| EP-1706414-A2 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005063786-A2 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | F.HOFFMAN-LA ROCHE AG (CH) | 2005-07-14 | — | — | WO | disclosed |
| US-20050137392-A1 | Process for producing N4-Acyl-5'-deoxy-5-fluorocytidine | ROCHE COLORADO CORPORATION (US) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137392-A1 | Process for producing N4-Acyl-5'-deoxy-5-fluorocytidine | RNGTT, DUT, DCK | PDE3A 4545/4885PDE4D 2997/4885SLC29A1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.