Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.69 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.69 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658855 | 0.91 | KMT2A (0.58) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL1885192 | 0.88 | MEN1 (0.71) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL1879895 | 0.85 | CXCR2 (0.65) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL1875397 | 0.83 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL1878682 | 0.83 | MEN1 (0.65) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL5950304 | 0.82 | MEN1 (0.72) | MEN1KMT2ANPC1MAPTRAB9A | |
| Triclocarban SCHEMBL30479188 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTRAB9A | |
| Triclocarban SCHEMBL68658 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTRAB9A | |
| Triclocarban SCHEMBL4978963 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTRAB9A | |
| Triclocarban SCHEMBL27313500 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053497-B | Preparation method and application of hydroxylated triclocarban | 香港浸会大学深圳研究院 | 2021-06-01 | — | — | CN | disclosed |
| CN-109053497-A | A kind of preparation method and application of hydroxylating triclocarban | 香港浸会大学深圳研究院 | 2018-12-21 | — | — | CN | disclosed |