Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883373 | 0.88 | CA12 (0.71) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL1879895 | 0.86 | CXCR2 (0.65) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL31206327 | 0.83 | MAPT (0.66) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL10710484 | 0.83 | MEN1 (0.77) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL4548129 | 0.83 | MAPT (0.66) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL28569820 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL1885192 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL4351611 | 0.82 | TRPV1 (0.62) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL11048619 | 0.80 | MEN1 (0.76) | MEN1KMT2ANPC1EPHX1EPHX2 | |
| SCHEMBL4741253 | 0.80 | MEN1 (0.76) | MEN1KMT2ANPC1EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110110958-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEOPLASIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2011-05-12 | — | — | US | claimed |
| WO-2009054878-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEOPLASIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2009-04-30 | — | — | WO | claimed |
| CN-109053497-B | Preparation method and application of hydroxylated triclocarban | 香港浸会大学深圳研究院 | 2021-06-01 | — | — | CN | disclosed |
| CN-109053497-A | A kind of preparation method and application of hydroxylating triclocarban | 香港浸会大学深圳研究院 | 2018-12-21 | — | — | CN | disclosed |
| US-20110110958-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEOPLASIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110110958-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEOPLASIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2011-05-12 | — | — | US | disclosed |
| WO-2009054878-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEOPLASIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110110958-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEOPLASIA | TP53, NUP205, ANXA5 | MEN1 2133/4885KMT2A 2664/4885NPC1 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.