Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP20 | Q9Y2K6 | 1/20 | 1.00 |
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448868 | 1.00 | USP20 (1.00) | USP20NFE2L2PRKACAPRKACGPRKACB | |
| SCHEMBL28569850 | 1.00 | USP20 (1.00) | USP20NFE2L2PRKACAPRKACGPRKACB | |
| SCHEMBL29200274 | 0.81 | USP20 (0.68) | USP20NFE2L2PRKACAPRKACGPRKACB | |
| SCHEMBL23885700 | 0.80 | USP20 (0.66) | USP20PRKACAPRKACGPRKACBPLA2G1B | |
| SCHEMBL23885095 | 0.71 | PLA2G1B (0.57) | USP20NFE2L2PRKACAPRKACGPRKACB | |
| SCHEMBL23885530 | 0.68 | USP20 (0.51) | USP20PRKACAPRKACGPRKACBPLA2G1B | |
| SCHEMBL23885618 | 0.68 | USP20 (0.51) | USP20PRKACAPRKACGPRKACBPLA2G1B | |
| SCHEMBL28385691 | 0.68 | USP20 (0.51) | USP20PRKACAPRKACGPRKACBPLA2G1B | |
| SCHEMBL30053023 | 0.68 | USP20 (0.51) | USP20PRKACAPRKACGPRKACBPLA2G1B | |
| SCHEMBL28385395 | 0.68 | USP20 (0.51) | USP20PRKACAPRKACGPRKACBPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117618421-A | Application of deubiquitinase USP20 inhibitor in preparation of medicines for treating Japanese encephalitis | 中国人民解放军海军军医大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117618421-A | Application of deubiquitinase USP20 inhibitor in preparation of medicines for treating Japanese encephalitis | 中国人民解放军海军军医大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-112870358-B | Use of deubiquitinase USP20 for reducing cholesterol synthesis and improving metabolic syndrome | 武汉大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-112870358-A | Use of deubiquitinase USP20 for reducing cholesterol synthesis and improving metabolic syndrome | 武汉大学 | 2021-06-01 | — | — | CN | disclosed |