Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP20 | Q9Y2K6 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 3/20 | 0.45 |
| ▸ | AS3MT | Q9HBK9 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PFKFB1 | P16118 | 3/20 | 0.40 |
| ▸ | PFKFB2 | O60825 | 2/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885530 | 0.79 | USP20 (0.51) | USP20PLA2G1BATG4BNSD2AS3MT | |
| SCHEMBL23885700 | 0.79 | USP20 (0.66) | USP20PLA2G1BATG4BNSD2AS3MT | |
| SCHEMBL30053023 | 0.79 | USP20 (0.51) | USP20PLA2G1BATG4BNSD2AS3MT | |
| SCHEMBL23885618 | 0.79 | USP20 (0.51) | USP20PLA2G1BATG4BNSD2AS3MT | |
| SCHEMBL28385395 | 0.79 | USP20 (0.51) | USP20PLA2G1BATG4BNSD2AS3MT | |
| SCHEMBL23885743 | 0.76 | KIF11 (0.55) | USP20PLA2G1BATG4BPRKACAPRKACG | |
| SCHEMBL30051948 | 0.76 | KIF11 (0.55) | USP20PLA2G1BATG4BPRKACAPRKACG | |
| SCHEMBL30254651 | 0.76 | NSD2 (0.48) | USP20PLA2G1BATG4BNSD2AS3MT | |
| SCHEMBL23885417 | 0.76 | NSD2 (0.48) | USP20PLA2G1BATG4BNSD2AS3MT | |
| SCHEMBL5857090 | 0.75 | PLA2G1B (0.77) | USP20PLA2G1BATG4BNSD2AS3MT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689907-B | Method for preparing 2-nitroindole derivative | 苏州大学 | 2020-05-01 | — | — | CN | disclosed |