Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558890 | 0.82 | KDM1A (0.39) | HIF1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL28561273 | 0.82 | GAA (0.42) | HIF1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL28556843 | 0.82 | GAA (0.42) | HIF1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL28553773 | 0.81 | KDM1A (0.38) | HIF1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL28558386 | 0.78 | KMT2A (0.43) | HIF1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL27474162 | 0.70 | PPARG (0.56) | HIF1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL28680453 | 0.70 | KMT2A (0.43) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL15447319 | 0.68 | ELANE (0.43) | HIF1AKDM1A | |
| SCHEMBL8282265 | 0.67 | MAPT (0.58) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL28518145 | 0.67 | KMT2A (0.49) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |