Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 7/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000733 | 0.88 | PPARG (0.58) | PPARGPPARALIPEKMT2ACYP17A1 | |
| SCHEMBL25736699 | 0.87 | PPARG (0.52) | PPARGPPARALIPEKMT2AMEN1 | |
| SCHEMBL25736722 | 0.84 | PPARG (0.54) | PPARGPPARALIPEKMT2AMEN1 | |
| SCHEMBL14068236 | 0.82 | TP53 (0.62) | KMT2AMEN1CYP17A1ALDH1A1MAPT | |
| SCHEMBL9390731 | 0.80 | TP53 (0.64) | BCL9CTNNB1LIPEKMT2AMEN1 | |
| SCHEMBL4636496 | 0.80 | LIPE (0.52) | PPARGPPARALIPEKMT2AMEN1 | |
| SCHEMBL1162988 | 0.80 | LIPE (0.52) | PPARGPPARALIPEKMT2AMEN1 | |
| SCHEMBL6665914 | 0.80 | LIPE (0.52) | PPARGPPARALIPEKMT2AMEN1 | |
| SCHEMBL27476119 | 0.80 | OPRK1 (0.66) | BCL9CTNNB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL19503080 | 0.80 | PPARG (0.55) | PPARGPPARACYP17A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161962-A | Sulphonic-acid-amide derivative | KONO PHARMACEUTICAL IND K K (JP) | 1997-10-15 | — | — | CN | claimed |