Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566754 | 0.85 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6058096 | 0.85 | HSD17B10 (0.55) | HSD17B10ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL29387320 | 0.85 | HSD17B10 (0.55) | HSD17B10ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL26962466 | 0.80 | HSD17B10 (0.60) | HSD17B10ALDH1A1RAB9ANPC1HTT | |
| SCHEMBL21177836 | 0.77 | KIT (0.61) | HSD17B10ALDH1A1KITRAB9AKMT2A | |
| SCHEMBL10966690 | 0.76 | HSD17B10 (0.55) | HSD17B10ALDH1A1RAB9ANPC1HTT | |
| SCHEMBL21216699 | 0.73 | CYP2C9 (0.45) | HSD17B10ALDH1A1KITRAB9AKMT2A | |
| SCHEMBL6057857 | 0.71 | LCK (0.68) | HSD17B10LCK | |
| SCHEMBL23629004 | 0.70 | CYP2C19 (0.55) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL27946812 | 0.70 | HSD17B10 (0.55) | HSD17B10CA2ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265471-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-06-04 | — | — | CN | disclosed |