Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570422 | 0.85 | HSD17B10 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9957845 | 0.84 | PIK3CA (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21925010 | 0.79 | NPC1 (0.41) | NPC1RAB9ALCKALDH1A1KDM4E | |
| SCHEMBL21062982 | 0.73 | NPC1 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23730805 | 0.72 | NPC1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29644660 | 0.71 | ALDH1A1 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9955853 | 0.71 | ALDH1A1 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22922699 | 0.70 | LCK (0.46) | MEN1KMT2ANPC1RAB9ALCK | |
| SCHEMBL20094458 | 0.70 | ALDH1A1 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3644443 | 0.70 | CA12 (0.45) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265471-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-06-04 | — | — | CN | disclosed |