SCHEMBL28570518

SCHEMBL28570518

CC(C)(C)OC(=O)C1C2CNCC1C(F)NC2F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 3/20 0.33
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2255341 0.86 SSTR4 (0.41) SSTR4MAPK1
SCHEMBL2255345 0.86 SSTR4 (0.41) SSTR4MAPK1
SCHEMBL2255338 0.86 SSTR4 (0.41) SSTR4MAPK1
SCHEMBL409182 0.72 CHRNB2 (0.42) MAPK1
SCHEMBL15170766 0.72 CHRNB2 (0.40) SSTR4MAPK1
SCHEMBL25225240 0.70 CHRNB2 (0.41) MAPK1
SCHEMBL27893276 0.70 CHRNB2 (0.41) MAPK1
Hydrochloric Acid SCHEMBL2281859 0.70 CHRNB2 (0.41) MAPK1
SCHEMBL29119686 0.69
Iodide SCHEMBL1484659 0.69 CHRNB2 (0.39) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112867712-A Carboxamides as ubiquitin-specific protease inhibitors 瓦洛早期发现股份有限公司 2021-05-28 CN disclosed