Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24750151 | 0.84 | ACE (0.40) | ACERIPK1P2RX7MAPK1BRD4 | |
| SCHEMBL28576083 | 0.80 | ACE (0.56) | ACERIPK1P2RX7 | |
| SCHEMBL1637995 | 0.79 | P2RX7 (0.40) | ACEP2RX7MAPK1BRD4 | |
| SCHEMBL1637768 | 0.76 | P2RX7 (0.47) | ACEP2RX7MAPK1BRD4 | |
| SCHEMBL1638078 | 0.74 | P2RX7 (0.42) | ACERIPK1P2RX7MAPK1BRD4 | |
| SCHEMBL1636116 | 0.72 | P2RX7 (0.46) | ACEP2RX7MAPK1 | |
| SCHEMBL28568069 | 0.72 | ACE (0.54) | ACERIPK1BRD4 | |
| SCHEMBL28968201 | 0.71 | HPGD (0.43) | ACERIPK1 | |
| SCHEMBL13928519 | 0.69 | NR1H2 (0.37) | MAPK1BRD4 | |
| SCHEMBL3326606 | 0.68 | HRH3 (0.42) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105713068-B | Method for preparing imidapril key intermediate and derivative thereof | 湖南九典制药股份有限公司 | 2021-04-20 | — | — | CN | disclosed |