Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700868 | 0.87 | EPHA2 (0.47) | LMNAMAPTPOLBALDH1A1DRD4 | |
| SCHEMBL29262728 | 0.87 | EPHA2 (0.47) | LMNAMAPTPOLBALDH1A1DRD4 | |
| SCHEMBL1870183 | 0.85 | KMT2A (0.44) | LMNADRD4CA1CA2PDK1 | |
| SCHEMBL1700726 | 0.83 | HRH3 (0.46) | LMNAMAPTPOLBALDH1A1DRD4 | |
| SCHEMBL1957014 | 0.81 | MAPT (0.54) | LMNAMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL1957016 | 0.81 | MAPT (0.54) | LMNAMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL27910638 | 0.81 | MAPT (0.54) | LMNAMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL27893534 | 0.81 | MAPT (0.54) | LMNAMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL30467955 | 0.79 | LMNA (0.45) | LMNAMAPTPOLBALDH1A1CA12 | |
| SCHEMBL1700104 | 0.79 | LMNA (0.45) | LMNAMAPTPOLBALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661751-A | Heterocyclic compounds as BCL-2 inhibitors | 南京天印健华医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |