Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL15203964 | 0.87 | PTPN11 (0.49) | PTPN11BIDMCL1BCL2L1BAK1 | |
| Salicylic Acid SCHEMBL30211364 | 0.87 | PTPN11 (0.49) | PTPN11BIDMCL1BCL2L1BAK1 | |
| SCHEMBL342807 | 0.84 | PTPN11 (0.52) | PTPN11PPARATSHRTP53CYP3A4 | |
| SCHEMBL11330301 | 0.84 | PTPN11 (0.52) | PTPN11PPARATSHRTP53CYP3A4 | |
| SCHEMBL2467712 | 0.82 | HSPA5 (0.47) | TP53ALDH1A1 | |
| SCHEMBL29378735 | 0.82 | TSHR (0.58) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL25420946 | 0.81 | PTPN11 (0.50) | PTPN11BIDMCL1BCL2L1BAK1 | |
| SCHEMBL368881 | 0.81 | BID (0.50) | PTPN11BIDMCL1BCL2L1BAK1 | |
| SCHEMBL7078027 | 0.81 | BID (0.54) | PTPN11BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5453797 | 0.81 | BID (0.54) | PTPN11BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108778245-B | A method for micronizing and/or targeting pharmaceutically active ingredients to synovial tissue | 美蒂森 | 2022-05-13 | — | — | CN | disclosed |
| CN-107406429-B | Pyridazinone derivatives and their use in the treatment of cancer | 基因泰克公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-107074823-B | Therapeutic compounds and uses thereof | 基因泰克公司 | 2021-05-04 | — | — | CN | disclosed |