Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | BID | P55957 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL15203964 | 1.00 | PTPN11 (0.49) | PTPN11BIDMCL1BCL2L1BAK1 | |
| SCHEMBL11330301 | 0.92 | PTPN11 (0.52) | PTPN11PPARAALDH1A1TSHRLMNA | |
| SCHEMBL342807 | 0.92 | PTPN11 (0.52) | PTPN11PPARAALDH1A1TSHRLMNA | |
| SCHEMBL29378735 | 0.92 | TSHR (0.58) | ALDH1A1TSHRLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL28572007 | 0.87 | PTPN11 (0.46) | PTPN11BIDMCL1BCL2L1BAK1 | |
| SCHEMBL29854564 | 0.87 | KMT2A (0.59) | PTPN11ALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL29860353 | 0.85 | ALDH1A1 (0.48) | PTPN11BIDMCL1BCL2L1BAK1 | |
| Salicylic Acid SCHEMBL29388219 | 0.85 | BID (0.46) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8208703 | 0.85 | F7 (0.52) | PTPN11BIDMCL1BCL2L1BAK1 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL30805746 | 0.84 | TSHR (0.54) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111182883-B | Nanoemulsion with neutralized fatty acid and method for producing same | 联合利华知识产权控股有限公司（NL） | 2023-01-13 | — | — | CN | disclosed |