Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464053 | 0.97 | PDGFRB (0.50) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL30039372 | 0.97 | PDGFRB (0.50) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL17944740 | 0.84 | PDGFRB (0.61) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL14603340 | 0.82 | L3MBTL1 (0.52) | CA1CA2RAB9ANPC1MAPT | |
| SCHEMBL12580354 | 0.80 | PDGFRB (0.66) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL12580402 | 0.80 | PDGFRB (0.66) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL12580362 | 0.80 | PDGFRB (0.66) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL12580411 | 0.80 | PDGFRB (0.66) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL28802343 | 0.80 | MEN1 (0.49) | CA12CA1CA2MAPTALDH1A1 | |
| SCHEMBL24658938 | 0.80 | L3MBTL1 (0.63) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876464-A | Organic material with heterocyclic structure and application thereof | 北京燕化集联光电技术有限公司 | 2021-06-01 | — | — | CN | disclosed |