SCHEMBL28572802

SCHEMBL28572802

N#Cc1cn(Cc2ccccc2)c2ccc(NC(=O)c3ccccn3)cc12

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
XDH P47989 14/20 0.73
GRM4 Q14833 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30464267 1.00 XDH (0.73) XDHGRM4
SCHEMBL28566556 0.90 XDH (0.69) XDH
SCHEMBL30464269 0.90 XDH (0.69) XDH
SCHEMBL30464263 0.89 XDH (0.70) XDH
SCHEMBL28570831 0.89 XDH (0.70) XDH
SCHEMBL28563940 0.87 XDH (0.65) XDHGRM4
SCHEMBL28432409 0.87 XDH (0.67) XDH
SCHEMBL30464264 0.87 XDH (0.65) XDHGRM4
SCHEMBL28574102 0.86 XDH (0.69) XDH
SCHEMBL28568027 0.86 XDH (0.77) XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920170-A N- (indole-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof 中国医科大学 2021-06-08 CN claimed
CN-112920170-A N- (indole-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof 中国医科大学 2021-06-08 CN disclosed